The Coordinating Center CC situated in Berne, Switzerland is the headquarters of ETOP IBCSG Partners Foundation and provides high quality support and operational know-how for all aspects of clinical trial conduct and translational research. The CC co-workers are responsible for the overall coordination of the trials as well as for safety and regulatory, pharmacovigilance, drug supply, medical expertise, translational research coordination, qualify of life, monitoring, quality assurance and audits, program for young patients and group administration. For thoracic trials, it also maintains project and data management.